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Chromosomes

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ALSoD is a joint project of World Federation of Neurology and European Network to Cure ALS. The work leading to these results has received funding from the European Community’s Health Seventh Framework Programme FP7/2007-2013 under grant agreement number 259867.
European ALS ConsortiumWorld Federation of Neurology

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Gene report of major ALS genes in ALSoD Relationship between ALS and FTD genes

View DetailsLocusGeneGene nameChromosome
SelectALS 1SOD1Cu/Zn superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))21q22.11
SelectALS 2ALS2amyotrophic lateral sclerosis 2 (juvenile) homolog (human). Alsin2q33.2
SelectALS 3ALS3Unknown18q21
SelectALS 4SETXSenataxin9q34.13
SelectALS 5SPG11spastic paraplegia 11 (autosomal recessive)15q14
SelectALS 6FUSfusion (involved in t(12;16) in malignant liposarcoma)16p11.2
SelectALS 7ALS7Unknown20p13
SelectALS 8VAPBVesicle-associated membrane protein-associated protein B20q13.33
SelectALS 9ANGAngiogenin14q11.1
SelectALS 10TARDBPTAR DNA binding protein1p36.22
SelectALS 11FIG4FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)6q21
SelectALS 12OPTNoptineurin10p13
SelectALS 13ATXN2ataxin 212q23-q24.1
SelectALS 14VCPvalosin-containing protein9p13
SelectALS 15UBQLN2ubiquilin 2Xp11.21
SelectALS 16SIGMAR1sigma non-opioid intracellular receptor 19p13
SelectALS 17CHMP2Bchromatin modifying protein 2B3p12.1
SelectALS 18PFN1profilin 117p13.3
SelectALS 19ERBB4v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 42q33.3-q34
SelectALS 20HNRNPA1heterogeneous nuclear ribonucleoprotein A112q13.1
SelectALS-FTD 1ALS-FTD1Unknown9q21-q22
SelectALS-FTD 2C9orf72chromosome 9 open reading frame 729p21.2
SelectALSUNC13Aunc-13 homolog A (C. elegans)19p13.12
SelectALSDAOD-amino-acid oxidase12q24
SelectALSDCTN1Dynactin2p13
SelectALSNEFHneurofilament, heavy polypeptide 200kDa, heavy chain22q12.1-q13.1
SelectALSPRPHperipherin12q12
SelectALSSQSTM1sequestosome 15q35
SelectALSTAF15TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa17q11.1-q11.2
SelectALSSPASTSpastin2p24
SelectALSELP3elongation protein 3 homolog (S. cerevisiae)8p21.1

View all ALS-Related genes in ALSoD (112)

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© Copyright 2007-2014 King's College London, The Institute of Psychiatry | Rewritten + Version 4.0 by Olubunmi Abel | Project coordinated by Prof Ammar Al-Chalabi