GENE OVERVIEW OF ANIMAL MODEL


GeneVcp
Gene Namevalosin-containing protein
Organism Namerat
Biological NameRattus norvegicus
Other Names 
ChromosomeChr5 q22
Genomic coordinates 


BIOINFORMATICS

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ALL PUBLICATIONS (34)

First_AuthorYearTitle
Acharya2010Liver cytochrome P450 3A endoplasmic reticulum-associated degradation: a major role for the p97 AAA ATPase in cytochrome P450 3A extraction into the cytosol.
Altier2010The Cav+¦ subunit prevents RFP2-mediated ubiquitination and proteasomal degradation of L-type channels.
Alzayady2005"Involvement of the p97-Ufd1-Npl4 complex in the regulated endoplasmic reticulum-associated degradation of inositol 1,4,5-trisphosphate receptors."
Besche2009Isolation of mammalian 26S proteasomes and p97/VCP complexes using the ubiquitin-like domain from HHR23B reveals novel proteasome-associated proteins.
Beuron2006Conformational changes in the AAA ATPase p97-p47 adaptor complex.
Briggs2008Analysis of nucleotide binding to P97 reveals the properties of a tandem AAA hexameric ATPase.
Cayli2011Interaction between Smad1 and p97/VCP in rat testis and epididymis during the postnatal development.
Dolan2011Decreases in valosin-containing protein result in increased levels of tau phosphorylated at Ser262/356.
Faouzi2007Characterization of the physiological turnover of native and inactivated cytochromes P450 3A in cultured rat hepatocytes: a role for the cytosolic AAA ATPase p97?
Gerhard2004"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Isakov2011Stalled proteasomes are directly relieved by P97 recruitment.
Jin2006Identification of novel proteins associated with both alpha-synuclein and DJ-1.
Kobayashi2002Functional ATPase activity of p97/valosin-containing protein (VCP) is required for the quality control of endoplasmic reticulum in neuronally differentiated mammalian PC12 cells.
Kobayashi2007Involvement of valosin-containing protein (VCP)/p97 in the formation and clearance of abnormal protein aggregates.
Koike2010Valosin-containing protein (VCP) in novel feedback machinery between abnormal protein accumulation and transcriptional suppression.
Kondo1997p47 is a cofactor for p97-mediated membrane fusion.
Mazzucchelli2009Proteomic and biochemical analyses unveil tight interaction of ataxin-3 with tubulin.
Meyer2000"A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways."
Meyer2002"Direct binding of ubiquitin conjugates by the mammalian p97 adaptor complexes, p47 and Ufd1-Npl4."
Mori-Konya2009p97/valosin-containing protein (VCP) is highly modulated by phosphorylation and acetylation.
Na2012Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
Ortak2011Expression of p97/VCP and ubiquitin during postnatal development of the degenerating rat retina.
Pleasure1993"Valosin-containing protein, VCP, is a ubiquitous clathrin-binding protein."
PÚcheur2002Phospholipid species act as modulators in p97/p47-mediated fusion of Golgi membranes.
Rabouille1998Syntaxin 5 is a common component of the NSF- and p97-mediated reassembly pathways of Golgi cisternae from mitotic Golgi fragments in vitro.
Roy2000Role of p97 and syntaxin 5 in the assembly of transitional endoplasmic reticulum.
Strausberg2002"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."
Uchiyama2002"VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo."
Uchiyama2006p37 is a p97 adaptor required for Golgi and ER biogenesis in interphase and at the end of mitosis.
Uchiyama2003The localization and phosphorylation of p47 are important for Golgi disassembly-assembly during the cell cycle.
Wang2011Valosin-containing protein and neurofibromin interact to regulate dendritic spine density.
Watts2004Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein.
Ye2003Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains.
Zhang1994Isolation and characterization of the principal ATPase associated with transitional endoplasmic reticulum of rat liver.