GENE OVERVIEW OF ANIMAL MODEL


GeneTardbp
Gene NameTAR DNA binding protein
Organism Namerat
Biological NameRattus norvegicus
Other Names 
ChromosomeChr5 q36
Genomic coordinates 


BIOINFORMATICS

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ALL PUBLICATIONS (30)

First_AuthorYearTitle
Bonaldo1996Normalization and subtraction: two approaches to facilitate gene discovery.
Budini2012Cellular model of TAR DNA-binding protein 43 (TDP-43) aggregation based on its C-terminal Gln/Asn-rich region.
Caccamo2010Age-dependent changes in TDP-43 levels in a mouse model of Alzheimer disease are linked to A+¦ oligomers accumulation.
Casafont2009TDP-43 localizes in mRNA transcription and processing sites in mammalian neurons.
Dasuri2011Amino acid analog toxicity in primary rat neuronal and astrocyte cultures: implications for protein misfolding and TDP-43 regulation.
Dayton2011Frontotemporal lobar degeneration-related proteins induce only subtle memory-related deficits when bilaterally overexpressed in the dorsal hippocampus.
Dominguez2010Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cells.
Freeman2007TAR-DNA binding protein 43 in Pick disease.
Gitcho2008TDP-43 A315T mutation in familial motor neuron disease.
Hebron2012Parkin ubiquitinates Tar-DNA binding protein-43 (TDP-43) and promotes its cytosolic accumulation via interaction with histone deacetylase 6 (HDAC6).
Herman2011+¦-amyloid triggers ALS-associated TDP-43 pathology in AD models.
Johnson2011Acute and chronically increased immunoreactivity to phosphorylation-independent but not pathological TDP-43 after a single traumatic brain injury in humans.
Kabashi2008TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis.
Kokoulina2010Caspase-cleaved transactivation response DNA-binding protein 43 in Parkinson's disease and dementia with Lewy bodies.
McKee2010TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy.
Nardo2011Amyotrophic lateral sclerosis multiprotein biomarkers in peripheral blood mononuclear cells.
Neumann2006Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Piaceri2011Clinical heterogeneity in Italian patients with amyotrophic lateral sclerosis.
Quadri2011Broadening the phenotype of TARDBP mutations: the TARDBP Ala382Thr mutation and Parkinson's disease in Sardinia.
Sephton2010Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes.
Shultz2003Gene expression analysis in response to lung toxicants: I. Sequencing and microarray development.
Sreedharan2008TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis.
Strausberg2002"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."
Swarup2011Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments.
Tong2013Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats.
Tremblay2011Accumulation of transactive response DNA binding protein 43 in mild cognitive impairment and Alzheimer disease.
Tsai2010Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U.
Yang2011Analysis of oxygen/glucose-deprivation-induced changes in SUMO3 conjugation using SILAC-based quantitative proteomics.
Yokota2010Effect of topographical distribution of +¦-synuclein pathology on TDP-43 accumulation in Lewy body disease.
Yokota2010Phosphorylated TDP-43 pathology and hippocampal sclerosis in progressive supranuclear palsy.