GENE OVERVIEW OF ANIMAL MODEL


GeneSqstm1
Gene Namesequestosome 1
Organism Namerat
Biological NameRattus norvegicus
Other NamesOsi|ZIP|ZIP3
ChromosomeChr10 q21
Genomic coordinates 


BIOINFORMATICS

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ALL PUBLICATIONS (27)

First_AuthorYearTitle
Besche2009Isolation of mammalian 26S proteasomes and p97/VCP complexes using the ubiquitin-like domain from HHR23B reveals novel proteasome-associated proteins.
Croci2002"ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2."
Cui2011Age-related changes in the function of autophagy in rat kidneys.
Diradourian2008Involvement of ZIP/p62 in the regulation of PPARalpha transcriptional activity by p38-MAPK.
Geetha2012"Sequestosome 1/p62, a scaffolding protein, is a newly identified partner of IRS-1 protein."
Geetha2005"TRAF6-mediated ubiquitination regulates nuclear translocation of NRIF, the p75 receptor interactor."
Geetha2005Lysine 63 polyubiquitination of the nerve growth factor receptor TrkA directs internalization and signaling.
Gerhard2004"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Gong1999Differential stimulation of PKC phosphorylation of potassium channels by ZIP1 and ZIP2.
Grasso2010"Zymophagy, a novel selective autophagy pathway mediated by VMP1-USP9x-p62, prevents pancreatic cell death."
Hirano2004Solution structure of atypical protein kinase C PB1 domain and its mode of interaction with ZIP/p62 and MEK5.
Kuusisto2001Ubiquitin-binding protein p62 expression is induced during apoptosis and proteasomal inhibition in neuronal cells.
Lange2005The kinase domain of titin controls muscle gene expression and protein turnover.
Laurin2002Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of bone.
Myeku2011Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62.
Nakaso1999Effects of kainate-mediated excitotoxicity on the expression of rat counterparts of A170 and MSP23 stress proteins in the brain.
Nakaso2004Transcriptional activation of p62/A170/ZIP during the formation of the aggregates: possible mechanisms and the role in Lewy body formation in Parkinson's disease.
Puls1997"Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein."
Rivera2010Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic +¦-cells: protective role of p62-positive cytoplasmic inclusions.
Samuels2001Nerve growth factor stimulates the interaction of ZIP/p62 with atypical protein kinase C and targets endosomal localization: evidence for regulation of nerve growth factor-induced differentiation.
Strausberg2002"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."
Stumptner2002Mallory body--a disease-associated type of sequestosome.
Urbanczyk2010"PKC+Â-interacting protein ZIP3 is generated by intronic polyadenylation, and is expressed in the brain and retina of the rat."
Urbanczyk2011Spartin recruits PKC-+Â via the PKC-+Â-interacting proteins ZIP1 and ZIP3 to lipid droplets.
Wooten2008Essential role of sequestosome 1/p62 in regulating accumulation of Lys63-ubiquitinated proteins.
Wooten2001The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor.
Wooten2005The p62 scaffold regulates nerve growth factor-induced NF-kappaB activation by influencing TRAF6 polyubiquitination.