Gene Namesigma non-opioid intracellular receptor 1
Organism Namerat
Biological NameRattus norvegicus
Other NamesOprs1
ChromosomeChr5 q22
Genomic coordinates 


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Alonso2000Immunocytochemical localization of the sigma(1) receptor in the adult rat central nervous system.
Aydar2002The sigma receptor as a ligand-regulated auxiliary potassium channel subunit.
Bhuiyan2010Stimulation of Sigma-1 receptor by dehydroepiandrosterone ameliorates hypertension-induced kidney hypertrophy in ovariectomized rats.
Fontanilla2009"The hallucinogen N,N-dimethyltryptamine (DMT) is an endogenous sigma-1 receptor regulator."
Fu2010Sigma-1 receptors amplify dopamine D1 receptor signaling at presynaptic sites in the prelimbic cortex.
Gerhard2004"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Hayashi2001Regulating ankyrin dynamics: Roles of sigma-1 receptors.
Hayashi2007Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival.
Hayashi2004Sigma-1 receptors at galactosylceramide-enriched lipid microdomains regulate oligodendrocyte differentiation.
Hayashi2012The lifetime of UDP-galactose:ceramide galactosyltransferase is controlled by a distinct endoplasmic reticulum-associated degradation (ERAD) regulated by sigma-1 receptor chaperones.
Herrera2008sigma-1 receptor modulation of acid-sensing ion channel a (ASIC1a) and ASIC1a-induced Ca2+ influx in rat cortical neurons.
Klouz2007"Protection of cellular and mitochondrial functions against liver ischemia by N-benzyl-N'-(2-hydroxy-3,4-dimethoxybenzyl)-piperazine (BHDP), a sigma1 ligand."
Liu2010Expression of sigma receptor 1 mRNA and protein in rat retina.
Lu2012¤â-1 Receptor agonist SKF10047 inhibits glutamate release in rat cerebral cortex nerve endings.
Martin-Fardon2012Effect of ¤âÔéü receptor antagonism on ethanol and natural reward seeking.
Mei2007Modulation of brainstem opiate analgesia in the rat by sigma 1 receptors: a microinjection study.
Mei2001Molecular cloning and pharmacological characterization of the rat sigma1 receptor.
Mei2002Sigma1 receptor modulation of opioid analgesia in the mouse.
Ola2001Expression pattern of sigma receptor 1 mRNA and protein in mammalian retina.
Palacios2004Immunohistochemical localization of the sigma1 receptor in Schwann cells of rat sciatic nerve.
Palacios2003Immunohistochemical localization of the sigma1-receptor in oligodendrocytes in the rat central nervous system.
Sabeti2011Ethanol exposure in early adolescence inhibits intrinsic neuronal plasticity via sigma-1 receptor activation in hippocampal CA1 neurons.
Sabino2011Activation of ¤â-receptors induces binge-like drinking in Sardinian alcohol-preferring rats.
Sabino2008The sigma-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking.
Seth1998Cloning and functional characterization of a sigma receptor from rat brain.
Strausberg2002"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."
Takebayashi2002Nerve growth factor-induced neurite sprouting in PC12 cells involves sigma-1 receptors: implications for antidepressants.
Takebayashi2004Sigma-1 receptors potentiate epidermal growth factor signaling towards neuritogenesis in PC12 cells: potential relation to lipid raft reconstitution.
Tchedre2008Sigma-1 receptor regulation of voltage-gated calcium channels involves a direct interaction.
Tsai2011Insights into the Sigma-1 receptor chaperone's cellular functions: a microarray report.
Tsai2009Sigma-1 receptors regulate hippocampal dendritic spine formation via a free radical-sensitive mechanism involving Rac1xGTP pathway.
Yagasaki2006Chronic antidepressants potentiate via sigma-1 receptors the brain-derived neurotrophic factor-induced signaling for glutamate release.
Zhang2011¤â receptor 1 is preferentially involved in modulation of N-methyl-D-aspartate receptor-mediated light-evoked excitatory postsynaptic currents in rat retinal ganglion cells.
Zhang2002Sigma receptors inhibit high-voltage-activated calcium channels in rat sympathetic and parasympathetic neurons.