GENE OVERVIEW OF ANIMAL MODEL


GeneNefh
Gene Nameneurofilament, heavy polypeptide
Organism Namerat
Biological NameRattus norvegicus
Other NamesNfh
ChromosomeChr14 q21
Genomic coordinates 


BIOINFORMATICS

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ALL PUBLICATIONS (19)

First_AuthorYearTitle
Al-Chalabi1999Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis.
Anderson2008The phosphorylated axonal form of the neurofilament subunit NF-H (pNF-H) as a blood biomarker of traumatic brain injury.
Breen1988Partial sequence of the rat heavy neurofilament polypeptide (NF-H). Identification of putative phosphorylation sites.
Chin1990Transfected rat high-molecular-weight neurofilament (NF-H) coassembles with vimentin in a predominantly nonphosphorylated form.
Dautigny1988The large neurofilament subunit (NF-H) of the rat: cDNA cloning and in situ detection.
Elder1998Requirement of heavy neurofilament subunit in the development of axons with large calibers.
Fornaro2008Neuronal intermediate filament expression in rat dorsal root ganglia sensory neurons: an in vivo and in vitro study.
Garcia2003"NF-M is an essential target for the myelin-directed outside-in"" signaling cascade that mediates radial axonal growth."""
Kesavapany2007Inhibition of Pin1 reduces glutamate-induced perikaryal accumulation of phosphorylated neurofilament-H in neurons.
Lees1988The structure and organization of the human heavy neurofilament subunit (NF-H) and the gene encoding it.
Lieberburg1989"Cloning of a cDNA encoding the rat high molecular weight neurofilament peptide (NF-H): developmental and tissue expression in the rat, and mapping of its human homologue to chromosomes 1 and 22."
Liu2011Neuregulin-1+¦ regulates outgrowth of neurites and migration of neurofilament 200 neurons from dorsal root ganglial explants in vitro.
Robinson1986Isolation of a cDNA for the rat heavy neurofilament polypeptide (NF-H).
Rudrabhatla2008Pin1-dependent prolyl isomerization modulates the stress-induced phosphorylation of high molecular weight neurofilament protein.
Sasaki2002In vivo and in vitro phosphorylation at Ser-493 in the glutamate (E)-segment of neurofilament-H subunit by glycogen synthase kinase 3beta.
Takahashi2012The involvement of neurofilament heavy chain phosphorylation in the maturation and degeneration of rat oocytes.
Ueno2010Hyperphosphorylated neurofilament NF-H as a biomarker of the efficacy of minocycline therapy for spinal cord injury.
Yamamoto2008Characterization of primary sensory neurons mediating static and dynamic allodynia in rat chronic constriction injury model.
Zhang2012"Expression of mRNAs for PPT, CGRP, NF-200, and MAP-2 in cocultures of dissociated DRG neurons and skeletal muscle cells in administration of NGF or NT-3."