GENE OVERVIEW OF ANIMAL MODEL


GeneAls2
Gene Nameamyotrophic lateral sclerosis 2 (juvenile)
Organism Namerat
Biological NameRattus norvegicus
Other Names 
ChromosomeChr9 q31
Genomic coordinates 


BIOINFORMATICS

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ALL PUBLICATIONS (6)

First_AuthorYearTitle
Devon2005Cross-species characterization of the ALS2 gene and analysis of its pattern of expression in development and adulthood.
Jacquier2006Alsin/Rac1 signaling controls survival and growth of spinal motoneurons.
Masutani2008Molecular interaction of neurocalcin alpha with alsin (ALS2).
Topp2004Alsin is a Rab5 and Rac1 guanine nucleotide exchange factor.
Tudor2005ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth.
Yang2001"The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis."