GENE OVERVIEW OF ANIMAL MODEL


GeneDctn1
Gene Namedynactin 1
Organism Namemouse
Biological NameMus musculus
Other NamesGlued|p150|p150<glued>
ChromosomeChr6 35.94 cM
Genomic coordinates GRCm37Chr6:83165920-83200117 ( +)
Genomic coordinates GRCm38Chr6:83165920-83200117(+)


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ALL PUBLICATIONS (50)

First_AuthorYearTitle
Abe2008Dynactin is essential for growth cone advance.
Abe1997The presence of the 50-kDa subunit of dynactin complex in the nerve growth cone.
Carninci1999High-efficiency full-length cDNA cloning.
Carninci2000Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Carninci2005The transcriptional landscape of the mammalian genome.
Carson2005Axonal dynactin p150Glued transports caspase-8 to drive retrograde olfactory receptor neuron apoptosis.
Chan2002Targeted disruption of Huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior.
Colin2008Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons.
Gauthier2004Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
Hansen2008Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Harrison1995Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo.
Hashimoto-Tane2011Dynein-driven transport of T cell receptor microclusters regulates immune synapse formation and T cell activation.
Hutchins2010Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Jang1997Mouse p150Glued (dynactin 1) cDNA sequence and evaluation as a candidate for the neuromuscular disease mutation mnd2.
Jiang2001The effects of aging on gene expression in the hypothalamus and cortex of mice.
Katayama2005Antisense transcription in the mammalian transcriptome.
Kawai2001Functional annotation of a full-length mouse cDNA collection.
Kodani2013Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages.
Kuh2012Tubulin-binding cofactor B is a direct interaction partner of the dynactin subunit p150(Glued).
Lai2007The G59S mutation in p150(glued) causes dysfunction of dynactin in mice.
Lanctot2013Spatially dependent dynamic MAPK modulation by the Nde1-Lis1-Brap complex patterns mammalian CNS.
Lavi-Itzkovitz2012Functional consequences of necdin nucleocytoplasmic localization.
Levy2008Dynein drives nuclear rotation during forward progression of motile fibroblasts.
Lien2008Alpha-E-catenin binds to dynamitin and regulates dynactin-mediated intracellular traffic.
Liu2007"Retrolinkin, a membrane protein, plays an important role in retrograde axonal transport."
Liu2003BPAG1n4 is essential for retrograde axonal transport in sensory neurons.
Magnani2007Interaction of tau protein with the dynactin complex.
Morimoto2012"A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis."
Moughamian2012Dynactin is required for transport initiation from the distal axon.
Ng2012Disruption of the dynein-dynactin complex unveils motor-specific functions in osteoclast formation and bone resorption.
Nguyen2004A NUDEL-dependent mechanism of neurofilament assembly regulates the integrity of CNS neurons.
Ohbayashi2012Melanoregulin regulates retrograde melanosome transport through interaction with the RILP-p150Glued complex in melanocytes.
Okazaki2002"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
Piao2001Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.
Schlager2010Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis.
Shen2008Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells.
Shibata2000RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Skarnes2011A conditional knockout resource for the genome-wide study of mouse gene function.
Strausberg2002"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."
Stryke2003BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Vaughan1996Multiple mouse chromosomal loci for dynein-based motility.
Watahiki2005Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas.
Weber1998"High-resolution genetic, physical, and transcript map of the mnd2 region of mouse chromosome 6."
Wen2004EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration.
Yamada2009mNUDC is required for plus-end-directed transport of cytoplasmic dynein and dynactins by kinesin-1.
Ye2011LIS1 regulates osteoclast formation and function through its interactions with dynein/dynactin and Plekhm1.
Yu2010KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development.
Zambrowicz2003Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zhang2009SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.
Zheng2011[Location of Dctn1 in the mouse testis and sperm and its role in spermiogenesis].