GENE OVERVIEW OF KEY PUBLISHED STUDIES FOR ALS

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ANIMAL MODELS

KEY PUBLICATIONS (5) First_Author Year Title Paper Jackson 1996 Analysis of chromosome 5q13 genes in amyotrophic lateral sclerosis: homozygous NAIP deletion in a sporadic case Full_Paper Kunst 2000 Genetic mapping of a mouse modifier gene that can prevent ALS onset Full_Paper Orrell 1997 The relationship of spinal muscular atrophy to motor neuron disease: investigation of SMN and NAIP gene deletions in sporadic and familial ALS Full_Paper Parboosingh 1999 Deletions causing spinal muscular atrophy do not predispose to amyotrophic lateral sclerosis Full_Paper Pari 2000 Immunolocalization of NAIP in the human brain and spinal cord Full_Paper