GENE OVERVIEW OF KEY PUBLISHED STUDIES FOR ALS


GeneFGGY
Other namesFLJ10986; RP11-242B9.1; FGGY
Gene nameFLJ10986
Gene inheritanceSALS genes
Discovery methodGWAS
Category 
Chromosome1p32.1
GRCh37 (hg19)Chr1:59762625-60228402 ( +)
GRCh38 (hg38)Chr1:59296953-59762730(+)
BackgroundVariants of FLJ10986 may confer susceptibility to sporadic ALS
Result 
Mutations0
Patients0

BIOINFORMATICS

Entrez Gene  UCSC Browser  Protein Structure  OMIM  Genecards  Full Literature  ProtScale  Sequence    Uniprot
iHop  Pathway  GeneTest  ALS review                  Animal models
GeneMANIA  AmiGO  Gene Wiki  Wolfram Alpha  Ensembl  NCBI  WikiGenes  Life Science DB(Japan)  ALSGene    GeneNetwork
Gen2Phen   LOVD   Orphanet Human Proteome Map Proteomics DB ALS Data Browser

ANIMAL MODELS

                               

KEY PUBLICATIONS (4)

First_AuthorYearTitlePaper
Daoud2010Analysis of DPP6 and FGGY as candidate genes for amyotrophic lateral sclerosisFull_Paper
Daoud2010Resequencing of 29 Candidate Genes in Patients With Familial and Sporadic Amyotrophic Lateral SclerosisFull_Paper
Dunckley2007Whole-genome analysis of sporadic amyotrophic lateral sclerosisFull_Paper
van Es2009Analysis of FGGY as a risk factor for sporadic amyotrophic lateral sclerosisFull_Paper

GENETIC VARIATIONS

SNP (rs)BasepairpvalueAuthorYearTermPaper
  0.38Daoud2010GRCh37Resequencing of 29 Candidate Genes in Patients With Familial and Sporadic Amyotrophic Lateral Sclerosis
 60228238 Daoud2010GRCh37Resequencing of 29 Candidate Genes in Patients With Familial and Sporadic Amyotrophic Lateral Sclerosis
 835435598444710.19Daoud2010GRCh37Resequencing of 29 Candidate Genes in Patients With Familial and Sporadic Amyotrophic Lateral Sclerosis
 6700125594148180.0006Dunckley2007GRCh37Whole-genome analysis of sporadic amyotrophic lateral sclerosis
 6690993594160030.0003Dunckley2007GRCh37Whole-genome analysis of sporadic amyotrophic lateral sclerosis