GENE OVERVIEW OF KEY PUBLISHED STUDIES FOR ALS


GeneC1orf27
Other namesODR4; TTG1; odr-4; FLJ20505; C1orf27
Gene namechromosome 1 open reading frame 27
Gene inheritanceSALS genes
Discovery methodGWAS
Category 
Chromosome1q25
GRCh37 (hg19)Chr1:186344890-186390503 á( +)
GRCh38 (hg38)Chr1:186375758-186421371(+)
BackgroundTo further examine the frequency of mutations in TARDBP in sporadic ALS.
ResultSeveral genetic variants were identified in controls, which were considered as non-pathogenic changes
Mutations0
Patients0

BIOINFORMATICS

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ANIMAL MODELS

                               

KEY PUBLICATIONS (1)

First_AuthorYearTitlePaper
Guerreiro2008TDP-43 is not a common cause of sporadic amyotrophic lateral sclerosisFull_Paper