| Gene | SPG7 |
| Other names | CAR; PGN; CMAR; SPG5C; FLJ37308; MGC126331; MGC126332 |
| Gene name | spastic paraplegia 7 (pure and complicated autosomal recessive) |
| Gene inheritance category | SALS genes |
| Category | MITOCHONDRIAL DEFECTS |
| Chromosome | 16q24.3 |
| Genomic Coordinates | Chr16:89574805-89624174(+) |
| Background | Mutations in spastin and paraplegin are the most common causes of hereditary spastic paraparesis. Paraplegin is a nuclear encoded mitochondrial metalloprotease. |
| Result | No association demonstrated/ replicated with paraplegin |
| Total Mutations | 0 |
| Total Affected | 0 |