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GENE OVERVIEW OF KEY PUBLISHED STUDIES FOR ALS


GenePSEN1
Other namesAD3; FAD; PS1; S182; "Alzheimer disease 3"
Gene namepresenilin 1
Gene inheritance categorySALS genes
CategoryREGENERATION, TROPHISM AND MOTONEURONAL DEATH
Chromosome14q24.3
BackgroundPSEN1 involved in apoptosis, a postulated mechanism for neuronal death
ResultWeak association found, small study, not replicated
Total Mutations0
Total Affected0

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KEY PUBLICATIONS (1)

First_AuthorYearTitlePaper
Panas2000Genotyping of presenilin-1 polymorphism in amyotrophic lateral sclerosisFull_Paper

GENETIC VARIATIONS

SNP (rs)BasepairpvalueAuthorYearTermPaper
   Panas2000GRCh37Genotyping of presenilin-1 polymorphism in amyotrophic lateral sclerosis
        
 
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