GENE OVERVIEW OF KEY PUBLISHED STUDIES FOR ALS


GeneLIPC
Other namesHL; HTGL; LIPH; HDLCQ12; LIPC
Gene namelipase, hepatic
Gene inheritance categorySALS genes
Category 
Chromosome15q22.1
Genomic CoordinatesChr15:58724175-58861073 ( +)
BackgroundGenetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis
ResultLIPC has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake
Total Mutations0
Total Affected0

BIOINFORMATICS

Entrez Gene  UCSC Browser  Protein Structure  OMIM  Genecards  Full Literature  ProtScale  Sequence    Uniprot
iHop  Pathway  GeneTest  ALS review                  Animal models
GeneMANIA  AmiGO  Gene Wiki  Wolfram Alpha  Ensembl  NCBI  WikiGenes    ALSGene    GeneNetwork
Gen2Phen   LOVD   Orphanet Human Proteome Map Proteomics DB

ANIMAL MODELS

                               

KEY PUBLICATIONS (2)

First_AuthorYearTitlePaper
Penco2008New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic backgroundFull_Paper
van Es2007Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosisFull_Paper

GENETIC VARIATIONS

SNP (rs)BasepairpvalueAuthorYearTermPaper
 180058858723675 Penco2008GRCh37New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background